At Genesis Med Spa, we use personalized testing and targeted treatments to bring your hormones to their optimal levels — going beyond “normal” to enhance metabolism, sharpen mental clarity, and boost overall vitality. We address symptoms of PCOS as well as pre-, peri-, and post-menopause, with the goal of rejuvenating your life and helping you feel balanced and like yourself again. We treat low testosterone and manage erectile dysfunction, helping men reclaim their energy, confidence, and vitality to feel like themselves again.
Hormonal imbalances often develop gradually, with symptoms that can easily be mistaken for the effects of stress, aging, or a hectic lifestyle. Hormones are vital for regulating energy, mood, metabolism, and even muscle and tissue repair. When essential hormones such as testosterone, estrogen, thyroid, or growth hormone decline, the impact can be felt in many areas — from weight and stamina to mental sharpness and recovery time. Your hormone therapy replacement plan will be tailored to meet the needs of your body and help you get rid of the uncomfortable symptoms you are experiencing.
With bioidentical hormone replacement therapy, patients experience relief of these symptoms as well as additional benefits, such as improved libido, mental focus, and reduced risk of disease. The primary goal of hormone therapy is to address the root cause of these symptoms—hormone imbalance—and reach a state of hormone optimization.
Bioidentical hormone therapy pellets are custom-compounded estradiol or testosterone pressed into small, solid cylinders similar to a large grain of rice. Pellet production is highly regulated by the FDA. EvexiPEL Certified providers, (our very own Nurse Practitioner, Abbi) source pellets from FaramKeio, one of the leading 503B FDA-registered compounding pharmacies in the country. Each pellet is carefully compounded to the exact dose prescribed by your practitioner to meet your body’s unique needs and facilitate optimal absorption of your prescribed therapy.
Pellet therapy offers a safe, convenient, and effective way to restore hormone balance. Each tiny pellet provides a consistent release of hormones—lasting 3–5 months in women and 4–6 months in men—closely mimicking the body’s natural, steady production. This steady delivery reduces the highs and lows seen with other methods, minimizing side effects and improving overall outcomes.
Compared to creams, pills, patches, or injections, pellets are far more convenient. Pills and creams rely on daily use and can easily be over or under applied. Injections often deliver too much hormone at first, then taper off too quickly. Patches may fall off or irritate the skin. These fluctuations in hormone levels can worsen symptoms or cause unwanted side effects. With pellets, once inserted, they dissolve naturally, providing consistent relief. Most patients feel significant improvement after two treatments.
The steady delivery of hormones not only relieves symptoms but also supports long-term health, helping reduce certain risks associated with hormone imbalance. Unlike some other therapies, properly administered pellets do not increase the risk of blood clots.
Pellet therapy has been safely used since the 1930s and remains one of the most effective options for patients who have not had success with other forms of hormone replacement.
Initial blood work is performed to establish baseline hormone levels, aid in diagnosing AIS, and assess any imbalances in other major hormone systems (e.g., adrenal, thyroid). These values will help determine your initial dosage.
Four weeks after your first pellet insertion, you will have repeat labs (a smaller panel). These results will be reviewed at your six-week follow-up visit.
Thereafter, a full panel of labs is drawn annually. If you experience any significant changes in symptoms related to hormone therapy, your nurse practitioner will recommend reassessment at that time.
Pellets are inserted using a very minor surgical procedure, performed in the office setting and requiring only local anesthesia. Using a very small incision (~ 1-2 cm in women, ~ 3-4 cm in men), they are inserted subcutaneously below the belt and above the buttock in women, and in the posterior flank in men. Recovery is very quick and uncomplicated; exercise restrictions for 3 days in women and 5 days in men are simply to avoid complications.
For women, the effects typically last an average of 3-4 months. Very active individuals may require therapy every 3 months or sooner, while less active or elderly individuals may experience benefits for longer than 4 months. In men, the typical cycle ranges from 4-6 months. The return of early symptoms of hormone insufficiency, such as fatigue, joint pain, or decreased libido, can indicate the need for your next insertion.
Not at all. Certain types may have an influence on therapy, which your physician/provider will review with you.
There are no serious or permanent side effects. In some cases, nuisance side effects can occur, such as hair growth or acne, both of which are very treatable.
Transitioning to pellet therapy from other forms of HRT (Hormone Replacement Therapy) is common. Your physician can assess your needs even if you’re currently using another type of hormone replacement therapy. If you prefer to continue with your current HRT but are not ready for pellets, we can offer alternative formulations.
